498 | Dr. Kyle Gillett | Optimizing Testosterone: Interpreting Labs and Choosing the Right Treatment

Dr. Kyle Gillett joins Dr. Erin to break down the physiology behind testosterone regulation, including how SHBG, free versus total testosterone, and androgen receptor sensitivity influence symptoms, metabolic health, and treatment decisions. They discuss why men with similar lab values can feel very different, how lifestyle and insulin resistance affect hormone metabolism, and when tools like TRT or aromatase inhibitors are actually warranted. This episode focuses on practical, evidence-based mechanisms that help patients and clinicians make informed choices about hormone optimization