Big 12 Week 10 PREVIEW: Biggest Games, Upset Alerts & Predictions

Week 10 of the 2026 college football season brings another loaded slate of Big 12 matchups as the conference race continues to heat up. BYU and Utah face off in a massive showdown with major implications at the top of the standings, while Arizona State looks to take care of business against Colorado. TCU heads to Arizona for a Friday night matchup, Texas Tech hosts West Virginia, and Oklahoma State takes on Kansas State. Which teams are positioned to make a move, where could an upset be brewing, and which games could have the biggest impact on the Big 12 race? We’re breaking down the biggest matchups, storylines and predictions heading into Week 10.

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