22 Jan 2026 02:00

Perimenopause: Understanding the Emotional, Cognitive, and Physical Changes

Perimenopause is the natural transition leading into menopause, marked by erratic fluctuations in estrogen and progesterone. These unpredictable shifts can trigger emotional, cognitive, and physical changes – often years before menopause officially begins. We spoke with Megan Spence, PsyD, PMH-C, a licensed clinical psychologist, about the whole-body experience of perimenopause, including mood and memory changes, the structural and social factors that place some groups at higher risk, available hormonal and non-hormonal treatments, lifestyle strategies that may help, and when – and how – to ask for support. Your symptoms matter, and you deserve informed, compassionate care.

Credits

  • Host: Neha Pathak, MD, FACP, DipABLM
  • Guest: Megan Spence, PsyD, PMH-C
  • Producer/Editor: Lauren Summers
  • Show Notes: Lauren Summers

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