29 Oct 2026 05:27
The Gary Null Show - 10-29-26
- Study: Pomegranate-Derived Compound May Address Heart Failure With Preserved Ejection Fraction
- Study finds lower rates of overweight among vegan-fed cats
- Researchers identify common nutritional supplement as potential treatment for psoriasis
- Vitamin C and Mistletoe Linked to Significantly Improved Survival in Breast Cancer Patients
- How everyday isolation is stealing our minds, landmark study reveals
A particular type of heart failure affects more than 3 million people. Heart failure with preserved ejection fraction occurs when the heart still pumps blood but struggles to relax and properly fill. The study tested the compound in animals and in engineered human heart tissue.
The compound activates a protein called PKGl?, which promotes relaxation of blood vessels and the heart muscle.
The compound also significantly improved heart function in human heart tissue engineered from stem cells, suggesting the effects in animal hearts could translate to humans. A separate account of the findings described the compound as improving heart function in animal models of HFpEF and in engineered human heart tissue.
Research has found that pomegranate polyphenols, like punicalagin, are metabolized by gut bacteria into urolithin A, a compound reported to reduce arterial plaque buildup and inflammation.
Study finds lower rates of overweight among vegan-fed cats
Griffith University (Australia), October 26 2026 (Eurekalert)
A large-scale survey has found cats fed vegan diets had lower rates of obesity and related health problems, than those fed conventional meat-based diets.
An online survey analysed veterinary assessments of 1,305 cats fed either conventional meat-based (90%) or vegan (10%) diets for at least one year.
After accounting for factorss, vegan-fed cats had 34% lower odds of being assessed as overweight.
Overweight and obesity are common in domestic cats, with veterinary studies estimating that around 30–60% of cats are overweight or obese. Excess weight is associated with a range of health problems, including arthritis, diabetes, urinary tract disease and reduced quality of life.
Carers feeding cats vegan diets also reported lower rates of body weight-related disorders such as osteoarthritis and other musculoskeletal and mobility problems.
Researchers identify common nutritional supplement as potential treatment for psoriasis State Key Laboratory of Biomedical Analysis (China), October 27 2026 (Eurekalert)
Researchers in China have discovered that the vitamin B5 derivative pantethine limits the activity of immune cells that are key contributors to autoimmune diseases such as psoriasis. The study, to be published in the Journal of Experimental Medicine (JEM), shows that pantethine prevents the development of psoriasis in mice and also helps alleviate the symptoms of psoriasis patients in a small-scale human trial.
Dendritic cells are specialized immune cells that help to coordinate the different parts of the immune system. They can engulf and present foreign antigens to activate highly specific T cells, as well as secrete a variety of immune signaling molecules to recruit other types of immune cells and promote inflammation. Because of this central role in directing immune responses, aberrant activation of dendritic cells is thought to underlie a variety of autoimmune diseases, including psoriasis.
The researchers found that the levels of metabolic enzymes known as Vanins are elevate
