When Sweet Turns Sour: The Risks of Artificial Sugars - Frankly Speaking Ep 457

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-457

Overview: Many patients turn to low- and no-calorie sweeteners to help with weight loss and lower diabetes risk, but do these alternatives actually deliver? In this episode, we review common artificial sweeteners and explore evidence on hunger, cardiovascular, diabetes, and dementia risks to understand how sugar substitutes can impact long-term health outcomes in your patients.

Episode resource links:

• fMRI Data: Nat Metab 7, 574–585 (2025). https://doi.org/10.1038/s42255-025-01227-8
• Adverse effects: Adv Nutr. 2023 Jul;14(4):710-717. doi: 10.1016/j.advnut.2023.05.010
• Dementia Data: Neurology® 2025;105:e214023. doi:10.1212/WNL.0000000000214023
• Stevia: Obes Rev. 2025 Jun;26(6):e13902. doi: 10.1111/obr.13902
• High Fructose Corn Syrup: Nutrition Reviews. 2021;79(2):209-226. doi:10.1093/nutrit/nuaa077

Guest: Robert A. Baldor MD, FAAFP

Music Credit: Matthew Bugos

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