11 Aug 2025 09:00

308: Fasting, Nicotine, and Microdosing LSD for Optimal Health Ft Sean McCormick

Have you ever considered dry fasting for five days to regenerate your body, or using a pendulum to shift energy and reduce pain? I'm sharing some wild ideas today.

I talked with Sean McCormick, host of the Optimal Performance podcast and a human guinea pig for health experiments. We discussed the kettlebell mile, a test of strength and endurance, and how grip strength predicts longevity. Sean shared insights on nicotine as a neuroprotectant and its effects. We explored the deep benefits of dry fasting, including muscle preservation and fat loss. Sean also described using a pendulum to harmonize energy and reduce pain. He shared his experiences with mini-dosing LSD for creativity and focus. I learned about the importance of N of one experiments for personal health journeys.

Key takeaways

  • Grip strength is an indicator of longevity, and tests like the kettlebell mile assess both strength and aerobic capacity.

  • A dopamine detox protocol can help reset your body and mental clarity.

  • Dry fasting for multiple days (without food or water) can regenerate the body on a cellular level, preserve muscle, and lead to significant fat loss, reaching deep ketosis and stem cell activation.

  • Nicotine has potential benefits as a neuroprotectant, nootropic, and may offer anti-bacterial or anti-parasitic properties, but it can be addictive and is a vasoconstrictor.

  • Oral TRT offers a different approach to testosterone replacement by providing mini-doses that may not hijack natural production.

  • Herbal supplements, like dried ants, are used in traditional practices for physical strength.

  • Pendulums made of magnetic metals can be used in energy medicine to harmonize energetic points, transmute negative energies, and potentially reduce pain.

  • Microdosing or mini-dosing psychedelics like LSD or psilocybin can enhance creativity, focus, and offer anti-inflammatory effects, and can improve cognition.

  • Conducting "N of one" experiments is a critical and fun way to learn about your own body's response to different health and fitness protocols.

Resources


Отзывы


Podcastly – the best platform for podcasters and podcast lovers. More than 10 millions of audio content that available on Android/iOS/Web/Desktop and Telegram.