
Charlotte Deane | Proteomics, AlphaFold 2, and Llamas #datascience #ai
Charlotte Deane (Oxford University) talks about statistical approaches to proteomics, the evolution of Google Deedmind's AlphaFold 2 & its place in proteomics' deep learning landscape, humanizing antibodies, and the increasing role of software engineers in research groups. The topic of llamas, camels, and alpacas (and their unique place in proteomics research) make a surprise visit.
Topics 0:00 Intro / An important topic to debate 3:50 What is a protein? Why are proteins foundational? 13:32 Immunotherapies, humanizing antibodies, & creating an scientific databases 16:04 Translating in silico research into immunotherapies 21:03 Nanobodies, camels, alpacas, & llamas. 25:05:00 Databases and data knowledge bases 33:21:00 Targeted therapies 39:45:00 Statistical modeling in proteomics 45:40:00 DeepMind AlphaFold's evolution 55:28:00 Software engineers in academic research groups 1:03:21 The adventure of science 1:07:42 Oxford Blues hockey & scientific debate