Episode 56: Initial Specimen Diversion Devices (ISDDs) for Preventing Blood Culture Contamination

In this episode of the ICHE Podcast, we explore the critical issue of blood culture contamination and the role of initial specimen diversion devices (ISDDs) in reducing false-positive results. Host Dr. David Calfee is joined by a distinguished panel of experts including: Dr. Maria Navas, Dr. Mark Rupp, Dr. Lucy Tompkins, and Dr. Francine Touzard Romo. The discussion begins with an overview of blood culture contamination—what it is, how it happens, and why it matters for patient care. Our experts examine the prevalence of contamination and its consequences, including unnecessary antibiotic use, prolonged hospital stays, and increased healthcare costs. The conversation then shifts studies recently published in ICHE on ISDDs—what they are, how they function, and whether they are an effective solution. Drs. Tompkins, Touzard Romo, and Navas share insights from their recent studies, followed by a discussion on the challenges of adherence in clinical settings. Dr. Rupp presents additional data to round out the discussion. At the conclusion of today’s episode, each expert offers a practical tip for healthcare professionals considering ISDD implementation in their institutions.