
In this special edition of the PBM Reform Podcast, host Greg Reybold welcomes nationally recognized drug pricing expert Antonio Ciaccia for an unfiltered conversation about pharmacy benefit managers (PBMs), hidden financial incentives, and the growing movement toward meaningful reform.
Ciaccia has spent years investigating the economics of prescription drug distribution, helping uncover hundreds of millions of dollars in questionable Medicaid drug spending and exposing the financial mechanisms behind inflated drug prices.
His latest work with 3 Axis Advisors raises important questions about whether conventional PBM contracts deliver the savings they promise.
An October 2026 analysis compares Mark Cuban Cost Plus Drug Company's published prices with traditional PBM pricing arrangements. Another June 2026 report examines how retrospective rebates, pricing benchmarks, and administrative arrangements create financial risks for employers and health plans.
Ciaccia has also described three forces capable of driving PBM reform: legislation, litigation, and market-based competition.
As he told Drug Topics, borrowing a familiar expression from Greg Reybold: “Pressure busts pipes.”
In This Episode
The future of pharmacy benefits depends on more than promises of reform. It demands transparency, accountability, and evidence that savings actually reach the people paying for healthcare.
Join Greg Reybold and Antonio Ciaccia as they follow the money and examine what's next for PBM reform.