Gut on a Chip: Human Gastrointestinal Organoids with Dr. Hyun Jung Kim

Dr. Hyun Jung Kim, an Assistant Professor at Cleveland Clinic specializes in coaxing human cultured cells to differentiate and form tissues resembling the gastrointestinal tract, in order to study microbe-GI interactions.  Dr. Kim discusses his surprising discovery of how common immortalized cultured cells can differentiate and form something that resembles a gut-on-a-chip, how these guts-on-a-chip can be used to study diseases like inflammatory bowel disease and colorectal cancer, how the addition of a microbiome to the gut-on-a-chip allows the bacteria to retain diversity unlike in a test tube, how the gut-on-a-chip could be valuable for personalized medicine, and the things he misses about Texas since moving from there. This episode was supported by Eezy Breezy Poke, an elegant at-home vaccine service.

Participants:

• Karl Klose, Ph.D. (UTSA)
• Hyun Jung Kim, Ph.D. (Cleveland Clinic)
• Janakiram Seshu, Ph.D. (UTSA)
• Jesus Romo, Ph.D. (UTSA)