Unlocking Cancer's Neural Code: A Deep (Molecular) Dive into Cancer Neuroscience with Trace-n-Seq

In this episode, we take a quick dive into the rapidly evolving field of cancer neuroscience. Joining us are Dr. Andreas Trumpp and Dr. Vera Thiel from DKFZ and HI-STEM, who introduce Trace-n-Seq, a groundbreaking technology that enables the molecular characterization of neurons within tumours at single-cell resolution. We discuss the application of this cutting-edge innovation in pancreatic cancer, from the insights it offers into neuron–cancer–microenvironment interactions, to the powerful clinical implications.

This episode focuses on the following publication in Nature (10.1038/s41586-025-08735-3), highlighted in a recent edition of the EACR’s Highlights in Cancer Research.

🔗 Read more about the publication: https://magazine.eacr.org/highlights-in-cancer-research-july-2025/9/

🔗 Access transcripts for all our episodes at magazine.eacr.org/podcast